HIPOMINERALIZA��O MOLAR-INCISIVO:  UM DESAFIO NA ROTINA DA ODONTOPEDIATRIA DO S�CULO XXI

Maristela Soares Swerts Pereira; Helo�sa de Sousa Gomes Rodrigues; N�dia Carolina Teixeira Marques; Kelma C�ntia Almada; Luana Dias Oliveira; Pietra Banhos Bruzadelli

HIPOMINERALIZA��O MOLAR-INCISIVO: UM DESAFIO NA ROTINA DA ODONTOPEDIATRIA DO S�CULO XXI

Maristela Soares Swerts Pereira, Helo�sa de Sousa Gomes Rodrigues, N�dia Carolina Teixeira Marques, Kelma C�ntia Almada, Luana Dias Oliveira, Pietra Banhos Bruzadelli

Resumo

A Hipomineraliza��o Molar-Incisivo (HMI) � um defeito de desenvolvimento do esmalte dent�rio, de origem sist�mica, desencadeado na amelog�nese durante o est�gio de matura��o. Resulta em quantidade normal do esmalte dent�rio, mas mineraliza��o deficiente, ou seja, � um defeito qualitativo que pode afetar de um at� os quatro primeiros molares permanentes, podendo estar ou n�o presente nos incisivos permanentes. � caracterizada por opacidades demarcadas, normalmente lisas e regulares que podem variar sua colora��o entre o branco, amarelo ou marrom. Segundo dados epidemiol�gicos, sua preval�ncia aumentou nos �ltimos anos, atingindo diferentes sexos, etnias e ra�as. Sua etiologia, ainda n�o definida, apresenta como poss�veis causas fatores ambientais e sist�micos, al�m da evid�ncia de fatores gen�ticos. Diante do diagn�stico da HMI a conduta cl�nica do Cirurgi�o-Dentista ir� depender da severidade do defeito e das sequelas decorrentes desta altera��o. Assim, considerando a HMI como um desafio na rotina da Odontopediatria e visando proporcionar melhor conhecimento e entendimento acerca dessa ocorr�ncia, este trabalho teve como objetivo efetuar uma revis�o de literatura, abordando sua preval�ncia, os poss�veis fatores etiol�gicos, caracter�sticas, diagn�sticos diferenciais, implica��es cl�nicas e tratamentos. Os artigos selecionados foram analisados na �ntegra e discutidos de maneira descritiva.�

Palavras-chave

Hipomineraliza��o Molar-Incisivo; Defeitos do desenvolvimento do esmalte; Opacidades demarcadas

Texto completo:

PDF

Refer?ncias

Paglia L. Molar Incisor Hypomineralization: paediatricians should be involved as well! Eur J Paediatr Dent. 2018 Sep;19(3):173. doi: 10.23804/ejpd.2018.19.03.01.

Barros de Alencar CR, Cavalcanti AL. Molar incisor hypomineralization - A challenge of Pediatric Dentistry? J Oral Res 2018; 7(3):84-5. doi:10.17126/joralres.2018.026.

da Cunha Coelho ASE, Mata PCM, Lino CA, Macho VMP, Areias CMFGP, Norton APMAP, Augusto APCM. J Esthet Restor Dent 2019 Jan;31(1):26-39. doi: 10.1111/jerd.12420.

Garot E, Denis A, Delbos Y, Manton D, Silva M, Rouas P. Are hypomineralised lesions on second primary molars (HSPM) a predictive sign of molar incisor hypomineralisation (MIH)? A systematic review and a meta-analysis. J Dent 2018 May;72:8-13. doi: 10.1016/j.jdent.2018.03.005.

Padavala S, Sukumaran G. Molar Incisor Hypomineralization and Its Prevalence. Contemp Clin Dent 2018;9(Suppl 2):S246S250. doi:10.4103/ccd.ccd_161_18.

Hubbard MJ, Mangum JE, Perez VA, Nervo GJ, Hall RK. Molar Hypomineralisation: A Call to Arms for Enamel Researchers. Front Physiol 2017 Aug;8:546. doi:10.3389/fphys.2017.00546.

Rao MH, Aluru SC, Jayam C, Bandlapalli A, Patel N. Molar Incisor Hypomineralization. Contemp Dent Pract 2016 Jul 1;17(7):609-13.

Dave M, Taylor G. Global prevalence of molar incisor hypomineralisation. Evid Based Dent 2018 19, 789 doi:10.1038/sj.ebd.6401324

Zhao D, Dong B, Yu D, Ren Q, Sun Y. The prevalence of molar incisor hypomineralization: evidence from 70 studies. Int J Paeditr Dent 2018 Mar;28(2):170-9. doi: 10.1111/ipd.12323.

Lygidakis NA, Wong F, J�levik B, Vierrou A-M, Alaluusua S, Espelid I. Best clinical practice guidance for clinicians dealing with children presenting with Molar-Incisor-Hypomineralisation (MIH): An EAPD Policy Document. Eur Arch Paediatr Dent 2010;11(2):75-81. doi.org/10.1007/BF03262716

Rodrigues FCN, Ribeiro PHB, Thomaz EBAF, Lima GQT, Neves PAMN, Ribeiro CCC. Molar-Incisor Hypomineralization in Schoolchildren of S�o Luis, Brazil Maranh�o: Prevalence and Associated Factors. Brazilian Research in Pediatric Dentistry and Integrated Clinic 2015;15(1):271-8. doi.org/10.4034/PBOCI.2015.151.29

Soviero V, Haubek D, Trindade C, da Matta T, Poulsen S. Prevalence and distribution of demarcated opacities and their sequelae in permanent teeth 1st molars and incisors in 7 to 13-years-old Brazilian children. Acta Odontol Scand 2009; 67(3):170-5. doi.org/10.1080/00016350902758607

Davenport M, Welles AD, Angelopoulou MV, et al. Prevalence of molar-incisor hypomineralization in Milwaukee, Wisconsin, USA: a pilot study. Clin Cosmet Investig Dent 2019;11:10917. doi:10.2147/CCIDE.S172736.

Reyes MR T, Fatturi AL, Menezes JVN B, Fraiz FC, Assun��o LRS, Souza JF. Demarcated opacity in primary teeth increases the prevalence of molar incisor hypomineralization. Braz Oral Res. [Internet]. 2019 [cited 2019 Nov 28] ; 33: e048. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242019000100254&lng=en. Epub Aug 15, 2019. http://dx.doi.org/10.1590/1807-3107bor-2019.vol33.0048.

Wong HM. Aetiological Factors for Developmental Defects of Enamel. Austin J Anat 2014; 1:1003. doi:10.1371/journal.pone.010935.

Sadashivamurthy P, Deshmukh S. Missing links of molar incisor hypomineralization: A review. J Int Oral Health 2012;4:111.

Reid DJ, Dean MC. Variation in modern human enamel formation times. J Hum Evol. 2006 Mar;50(3):329-46.

Biondi AM, Cortese SG, Babino L, Fridman DE. Comparison of Mineral Density in Molar Incisor Hypomineralization applying fluoride varnishes and casein phosphopeptide-amorphous calcium phosphate. Acta Odontol Latinoam. 2017 Dec;30(3):118-23.

Teixeira RJPB. et al. Exploring the association between genetic and environmental factors and molar incisor hypomineralization: evidence from a twin study. Int J Paediatr Dent 2017 Aug;28(2):198-206. doi: 10.1111/ipd.12327.

Bodrumlu EH , Avsar A. Molar incisor hypomineralization in children with systemic diseases. Srp Arh Celok Lek. 2019 Jan-Feb;147(1-2):17-22, doi.org/10.2298/SARH180118036B.

Crombie F, Manton D, Kilpatrick N. Aetiology of molar-incisor hypomineralization: a critical review. Int J Paediatr Dent 2009 Mar;19(2):7383. doi: 10.1111/j.1365-263X.2008.00966.x.

Fatturi AL et al. A systematic review and metaanalysis of systemic exposure associated with molar incisor hypomineralization. Community Dent Oral Epidemiol 2019 Oct;47(5):407-415. doi: 10.1111/cdoe.12467.

Hernandez M, Boj J, Espasa E, Planells P, Peretz B Molar-Incisor Hypomineralization: positive correlation with atopic dermatitis and food allergies. J Clin Pediatr Dent 2018 May; 42(5): 1-5. doi: 10.17796/1053-4625-42.5.4.

Silva MJ, Scurrah KJ, Craig JM, Manton DJ, Kilpatrick N. Etiology of molar incisor hypomineralization - A systematic review. Community Dent Oral Epidemiol 2016 Aug;44(4):342-53. doi: 10.1111/cdoe.12229.

Willmott NS, Bryan RA, Duggal MS. Molar-incisor-hypomineralisation: a literature review. Eur Arch Paediatr Dent 2008 Dec;9(4):172-9. doi: 10.1007/bf03262633

Vieira AR, Kup E. On the etiology of molar-incisor hypomineralization. Caries Res Basel 2016 May;50(2):166-9. doi.org/10.1159/000445128.

Biondi AM, C�rtese SG, Babino L, Toscano MA. Molar incisor hypomineralization: Analysis of asymmetry of lesions. Acta Odontol Latinoam 2019 Apr 1;32(1):44-48.

J�levik B, Nor�n JG. Enamel hypomineralization of permanent first molars: A morphological study and survey of possible aetiological factors. Int J Paediatr Dent 2000; 10(4):278-89. doi: 10.1046/j.1365-263x.2000.00210.x

da Costa-Silva CM, Ambrosano GMB, Jeremias F, Souza JF, Mialhe FL. Increase in severity of molarincisor hypomineralization and its relationship with the colour of enamel opacity: a prospective cohort study. Int J Paediatr Dent 2011:21:333-4. doi: 10.1111/j.1365-263X.2011.01128.x

Weerheijm KL. Molar incisor hypomineralisation (MIH). Eur J Paediatr Dent 2003;4:11420.

Jeremias F, de Souza JF, Silva CM, Cordeiro Rde C, Zuanon AC, Santos-Pinto L. Dental caries experience and molar-incisor hypomineralization. Acta Odontol Scand 2013 May/July; 71(3-4):870-6. doi: 10.3109/00016357.2012.734412.

Cabral RN, Nyvad B, Soviero VLVM, Freitas E, Leal SC. Reliability and validity of a new classification of MIH based on severity. Clin Oral Investig 2019 May 25. doi: 10.1007/s00784-019-02955-4.

Adorno-Farias D et al. Diversity of clinical, radiographic and genealogical findings in 41 families with amelogenesis imperfecta. J Appl Oral Sci 2019 Apr1;27:e20180359. doi: 10.1590/1678-7757-2018-0359.

Ghanim A et al. A practical method for use in epidemiological studies on enamel hypomineralization. Eur Arch Paediatr Dent 2015 June;16(3):235-46. doi 10.1007/s40368-015-0178-8.

Weerheijm KL. Molar incisor hypomineralization (MIH): clinical presentation aetiology and management. Dental Update 2004;31(1):9-12. doi 10.5005/jp-journals-10005-1164.

Garg N, Jain AK, Saha S, Singh J. Essentiality of early diagnosis of molar incisor hypomineralization in children and review of its clinical presentation, etiology and management. Int J Clin Pediatr Dent 2012; 5:190�196.

Patel A, Aghababaie S, Parekh S. Hypomineralisation or hypoplasia?. Br Dent J 2019; 227;6836 doi:10.1038/s41415-019-0782-9.

Americano GC, Jacobsen PE, Soviero VM, Haubek D. A systematic review on the association between molar incisor hypomineralization and dental caries. Int J Paediatr Dent. 2017 Jan;27(1):11-21. doi: 10.1111/ipd.12233.

da Costa-Silva C M, Mialhe FL. Considerations for clinical management of molar-incisor hypomineralization: A literature review. Rev Odont Ci�ncia 2012; 27(4): 333-8.

William V, Messer LB, Burrow MF. Molar incisor hypomineralization: review and recommendations for clinical management. Pediatr Dent 2006; 28:224-32.

Daly D, Waldron JM. Molar incisor hypomineralisation: clinical management of the young patient. J of the Irish Dental Association 2009:55 (2):83-6.

Harika R et al. A novel clinical approach for long-term retention and durability of resin restorations bonded to multiple developmental defects of enamel. J Int Soc Prev Community Dent 2016 Nov./Dec;6(6): 597-601. doi: 10.4103/2231-0762.195507.

Giannetti L et al. Deep infiltration for the treatment of hypomineralized enamel lesions in a patient with molar incisor hypomineralization: a clinical case. J Biol Regul Homeost Agents 2018 May/June;32(3):751-4.